Our group is exploring of how cardiogenesis as well as adult heart remodelling regulated.


In particular, we focus on the following topics:


  1. Exploring the signalling function of β-catenin and canonical WNT in mammalian heart development


  1. Understanding of canonical WNT signalling mechanisms: plakoglobin (γ- catenin) as potential transcriptional co-activator


  1. Beta catenin signalling function in adult heart remodelling (hypertrophy, regeneration, aging) and heart metabolism regulation


  1. Novel signalling function of αE-catenin in heart maturation and remodelling


  1. CRISPRa using for cardiomyogenic reprogramming of fibroblasts